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Reaches PFS, but OS numbers don't separate against placebo
December 12, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
ImmunoCellular Therapeutics (ICT) posted results from its randomized, placebo-controlled Phase II trial of dendritic cell-based vaccine ICT-107 in patients with newly diagnosed glioblastoma multiforme (GBM). The vaccine demonstrated a statistically significant increase in progression-free survival (PFS), but missed its primary endpoint of overall survival (OS), which was not statistically significant compared to placebo. Median progression-free survival times were two months longer for ICT-107 ...
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